Awesome
Awesome Python Models 
A curated list of awesome Python libraries, which implement models, schemas, serializers/deserializers, ODM's/ORM's, Active Records or similar patterns.
Model, Schema
Libraries implementing some kind of model, letting you to serialize/deserialize python object to some data structures.
- :ghost: ascetic - Ascetic, a lightweight Python datamapper ORM.
attrs - Python Classes Without Boilerplate.
booby - data modeling and validation Python library.
causalmodels - causal modeling in Python.
colander - A serialization/deserialization/validation library for strings, mappings and lists.
composite - Declarative XML files parse, unparse with help of lxml library.
datastore.objects - simple object mapper on top of datastore (not relational).
dirty-models - Dirty model for python.- dejavu - Dejavu is a thread-safe Object-Relational Mapper for Python applications.
gnarl - Lightweight module to define serializable, schema-validated classes
guts - Lightweight declarative YAML and XML data binding for Python.
jsonmapper - Python JSON<->Object mapper.
jsonmodels - jsonmodels is library to make it easier for you to deal with structures that are converted to, or read from JSON.
jsonobjects - jsonobjects allows you to declaratively specify how to extract and convert elements from a JSON document.
jsonobject - A simple json-object mapping for Python.- :ghost: jsonpickle - Python library for serializing any arbitrary object graph into JSON.
kim - A JSON Serialization and Marshaling framework.
lazycontract - Python library to define declarative contracts for serialization and deserialization.
lupin - Python document object mapper (load python object from JSON and vice-versa).
marshmallow - A lightweight library for converting complex objects to and from simple Python datatypes.- :ghost: metaparams - Python meta framework for Parameters in classes.
micromodels - Declarative dictionary-based model classes for Python.
monk - An unobtrusive data modeling, manipulation and validation library.
normalize - A toolkit for wrapping network data in Python objects.
model-api - For modeling remote APIs in an ORM fashion.
object-mapper - ObjectMapper is a class for automatic object mapping in Python.
param - Make your Python code clearer and more reliable by declaring Parameters.- :ghost: prettyrecord - Structures like SQLAlchemy's declarative_base or Django's models in your project!
pydantic - Data validation using Python 3.6 type hinting.
pyschema - Python library for class-based schema definition, object serialization and data validation.
python-json - Python library for easily JSON encoding/decoding complex class-based Python models, using an arbitrarily complex (but easy to write!) mapping schema.
python-docar - A library for document oriented architectures.
resource-api - A framework that allows developers decoratively define resources and relationships between them.
schematics - Python Data Structures for Humans™.
schema - A generic declarative schema system.
scheme - A declarative schema framework for Python.
simple-models - Simple models - keep your API messages in shape with validation and handy descriptors based object interface.
simple_model - a very simple model framework for python.
yorm - Automatic object-YAML mapping for Python.
ODM, ORM, Active Record
Libraries, implementing ODM/ORM/Active Record patterns, letting you to work with external objects (REST, DB) like normal python instances.
acid - SQLite for NoSQL.- :ghost: butterdb - butterdb is a Python object mapper for Google Drive Spreadsheets.
django - The Web framework for perfectionists with deadlines (includes ORM layer).-
finch - Asynchronous RESTful API consumer for Python.
flywheel - Object mapper for Amazon's DynamoDB.
kev - Python ORM for key-value stores. Currently supported backends are Redis, S3, and a S3/Redis hybrid backend.
modular-odm - A database-agnostic Object-Document Mapper for Python.
mongoengine - A Python Object-Document-Mapper for working with MongoDB.
orator - The Orator ORM provides a simple yet beautiful ActiveRecord implementation.
pony - Pony Object Relational Mapper.
peewee - a small, expressive orm -- supports postgresql, mysql and sqlite.
py-rest-orm - Generic Python REST ORM. Inspired by Django. Powered by Requests.
python-rest-model - A standard way to consume a RESTful service, inspired by Django models.
pyresto - A generic ORM framework for RESTful APIs.
pymodm - A Pythonic, object-oriented interface for working with MongoDB.
PynamoDB - A pythonic interface to Amazon's DynamoDB.
redisco - A Python Library for Simple Models and Containers Persisted in Redis.
remodel - Very simple yet powerful and extensible Object Document Mapper for RethinkDB, written in Python.
restorm - RestORM allows you to interact with resources as if they were objects.- :ghost: storm - Storm is an object-relational mapper (ORM) for Python developed at Canonical.
- :ghost: sqlobject - SQLObject is a popular Object Relational Manager for providing an object interface to your database, with tables as classes, rows as instances, and columns as attributes.
wukong - An ORM Client library for SolrCloud.
yadm - Yet Another Document Mapper (ODM) for MongoDB.
walrus - Lightweight Python utilities for working with Redis.
Data validation
Libraries for validating custom data structures.
cerberus - Lightweight, extensible data validation library for Python.
destructure - Easy declarative schema validation with optional name-binding.
jsonschema - jsonschema is an implementation of JSON Schema for Python (supporting 2.7+ including Python 3).
pyschemes - PySchemes is a library for validating data structures in Python.
pyvaru - Rule based data validation library for python 3.
required - Required is a simple library which allows you to validate dependencies across multiple fields.
schema - schema is a library for validating Python data structures, such as those obtained from config-files, forms, external services or command-line parsing, converted from JSON/YAML (or something else) to Python data-types.
strictyaml - Type-safe YAML parser and validator.
valideer - Lightweight data validation and adaptation Python library.
validr - A simple, fast, extensible python library for data validation.
voluptuous - Voluptuous, despite the name, is a Python data validation library. It is primarily intended for validating data coming into Python as JSON, YAML, etc.
Other resources
Other Awesome Lists
List of lists.
Contributing
If you know some project/library that is not listed here, just let me know! Or even better, create a pull request.