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BEHRT federated learning Implementation of the FederatedAveraging algorithm. Code of the paper: Federated Learning of Medical Concepts Embedding using BEHRT https://arxiv.org/abs/2305.13052

**If you used our code, please cite us: **

@article{shoham2023federated,
  title={Federated Learning of Medical Concepts Embedding using BEHRT},
  author={Shoham, Ofir Ben and Rappoport, Nadav},
  journal={arXiv preprint arXiv:2305.13052},
  year={2023}
}

FederatedAveraging algorithm proposed in the paper Communication-Efficient Learning of Deep Networks from Decentralized Data in PyTorch. Thanks to https://github.com/vaseline555/Federated-Learning-PyTorch for the initial code base.

Requirements

• See requirements.txt

Configurations

• See config.yaml data_dir_path: directory path that contains the multi-center data (csv files), BEHRT format. Each center data is one csv file. Example format: see behrt_nextvisit_example_data.csv test_path: path to test csv file, same format as behrt_nextvisit_example_data.csv. vocab_pickle_path: path to the pickle that contains the vocab.

You can you this script to create your pickle vocab: https://github.com/Ofir408/BEHRT/blob/master/preprocess/bert_vocab_builder.py

In order to create token2idx you can use the following script:

from typing import Dict
import json
import pandas as pd
from typing import List 

def get_all_codes(df: pd.DataFrame, codes_to_ignore: List[str]) -> List[str]:
    codes = []
    for df_list_codes in list(df['code']):
        codes.extend(df_list_codes)
    return list(set(codes) - set(codes_to_ignore))

def get_bert_tokens() -> Dict[str, int]:
    return {
      "PAD": 0,
      "UNK": 1,
      "SEP": 2,
      "CLS": 3,
      "MASK": 4,
    }
    
def build_token2index_dict(df: pd.DataFrame) -> Dict[str, int]:
    token2inx_dict = get_bert_tokens()
    next_index = max(token2inx_dict.values()) + 1
    
    codes = get_all_codes(df= df, codes_to_ignore=token2inx_dict.keys())
    for code in codes:
        token2inx_dict[str(code)] = next_index
        next_index += 1
    return token2inx_dict

def create_token2index_file(df: pd.DataFrame, output_file_path: str):
    token2inx_dict = build_token2index_dict(df= df)
    with open(output_file_path, 'w') as f:
        json.dump(token2inx_dict, f)
        print(f'token2inx was created, path={output_file_path}')

Run

1. Install Dependencies

   Run the following command to install the required packages: pip install -r requirements.txt

2. Preprocess MIMIC-IV Dataset:

   Use the provided notebook to preprocess the MIMIC-IV dataset: MIMIC-IV Feature Extraction Notebook

3. Train MLM via Federated Learning

   Switch to the fl_mlm_training branch for the training code: git checkout fl_mlm_training

4. Edit Configuration

   Modify the config.yaml file. Update the data_config section to reflect the paths of the datasets saved from the preprocessing notebook.

5. Run Training

   Start the training process by running: python main.py <path_to_config.yaml>

6. Switch back to the main branch to run the federated learning for the next visit prediction model: git checkout main

7. Update Configuration

   In the configuration file, set the pretrained_model_path to the federated learning MLM model saved from the previous step.

8. Run Next Visit Model Training

   Execute the training for the next visit model: python main.py <path_to_config.yaml>