Awesome

Protein Structure Landscape

This repository contains data, scripts and notebooks for the analysis of the protein structure landscape described in:

Szczerbiak P, Szydlowski L, Wydmański W, Renfrew PD, Koehler Leman J, Kosciolek T. Large protein databases reveal structural complementarity and functional locality. bioRxiv, https://doi.org/10.1101/2024.08.14.607935 (2024).

Novel methods

The source code for new methods and tools developed during the research is available in dedicated data repositories:

• go2cog
• deepFRI v1.1
• web server

Web server

The web server is available at: https://protein-structure-landscape.sano.science.

It currently allows for:

• structure search by ID
• structure visualization with PyMOL
• filtering based on:
  • database (AFDB, ESMAtlas, MIP)
  • superCOG functional category
  • protein length
  • pLDDT (for AFDB models only)

The web server will be continuously improved.