Awesome

schubness

This repository contains the data and the scripts used in the manuscript "Hubness reduction improves downstream analyses of single-cell transcriptomic data" in which we study the hubness phenomenon and related observations in single-cell RNA sequencing data.

Aims

1. Evaluate hubs in sequencing data

(1a) Measuring hubness & define hubs

(1b) Study the nature of hubs & antihubs

(1c) Understand the parameters influencing hubness

2. Take advantage of hubs to improve the analysis

(2a) Clustering

(2b) Trajectory Inference

(2c) Visualisation

Scripts

All scripts used to produced the figures in the manuscript are available in this repository and are organized by experiment and by language (either R or python).

Data

We used public datasets and regrouped them in a Zenodo repository here.